Pharmacology In Drug Discovery And Development

Once a target is validated, high-throughput screening finds "hits" (molecules that bind to the target). But binding isn’t enough. Pharmacologists step in to define the relationship.

By studying —how a person's genetic makeup affects their response to drugs—pharmacologists can now predict who will benefit from a drug and who might suffer toxic side effects. pharmacology in drug discovery and development

This article dissects the multifaceted role of pharmacology across the entire value chain of drug creation, from target identification to post-marketing surveillance. Once a target is validated, high-throughput screening finds

The future of pharmacology in drug discovery and development holds much promise, with several areas expected to shape the field: Once a target is validated

This accelerates lead optimization from months to days. However, pharmacology remains needed to validate in silico predictions with wet-lab assays.