To play a God of War 2 ISO on modern hardware, you will generally use an emulator like for Android. PC Emulator (PCSX2) Minimum CPU
Download a version (approx 2.5 GB to 3 GB) rather than an "Ultra" (700 MB). This retains the audio quality and cutscene resolution while still being manageable for most devices. God Of War 2 Ps2 Iso Highly Compressed
: PCSX2 for PC (Windows/macOS/Linux) or AetherSX2/DamonPS2 for Android. To play a God of War 2 ISO