: A sweeping epic following Monkey D. Luffy and his pirate crew in search of the world's ultimate treasure. Known for its world-building and longevity, it is a staple of IMDb's Top Anime and a consistent bestseller on Amazon Fullmetal Alchemist: Brotherhood
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: Widely considered one of the greatest anime ever made, focusing on two brothers using alchemy to restore their bodies. : A sweeping epic following Monkey D
For those who prefer reading, these are the most successful manga series based on Wikipedia's sales data : Manga Series Approximate Sales Eiichiro Oda 600 Million+ Fujiko F. Fujio 300 Million Takao Saito 300 Million Case Closed (Detective Conan) Gosho Aoyama 270 Million The "Big Three" Evolution of the Genre : Widely considered one